Prognostic Value of Soluble ST2 in the Valsartan Heart Failure Trial Anand et al: sST2 in Heart Failure
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Prognostic Value of Soluble ST2 (sST2) Serum Levels in Infants and Children with Heart Failure Complicating Congenital Heart Disease
Background Heart failure (HF) in infants and children with congenital heart disease (CHD) is a crucial complication with different outcomes. Many biomarkers are used as prognostic indicators. Soluble ST2 (sST2) is one of these markers studied in adults with HF. We aimed to study the prognostic value of sST2 in CHD children with HF. Materials and Methods In current case-control study, thirty-six...
متن کاملPrognostic value of soluble ST2 in the Valsartan Heart Failure Trial.
BACKGROUND Soluble ST2 (sST2), a biomarker related to inflammation, is associated with outcomes of patients with heart failure. In-depth analyses of the relationship among sST2, changes in sST2, and patient outcomes are reported. METHODS AND RESULTS sST2 was measured at baseline (n=1650), 4 months (n=1345), and 12 months (n=1094) in Valsartan Heart Failure Trial. Baseline sST2 averaged 28.7±1...
متن کاملThe Prognostic Value of Plasma Soluble ST2 in Hospitalized Chinese Patients with Heart Failure
BACKGROUND sST2 has been shown to be a risk predictor in heart failure (HF). Our aim was to explore the characteristics and prognostic value of soluble ST2 (sST2) in hospitalized Chinese patients with HF. METHODS AND RESULTS We consecutively enrolled 1528 hospitalized patients with HF. Receiver operating characteristic (ROC) and multivariable Cox proportional hazards analysis were used to ass...
متن کاملSoluble ST2 Has a Prognostic Role in Patients With Suspected Sepsis
BACKGROUND Soluble suppression of tumorigenicity 2 (sST2) has emerged as a novel biomarker for heart failure, and serum sST2 concentrations could be increased in inflammatory diseases. We explored whether sST2 is related to cardiac dysfunction/failure and has a prognostic role in patients with suspected sepsis. METHODS In a total of 397 patients with suspected sepsis, sST2 concentrations were...
متن کاملSoluble ST2 protein in the short-term prognosis after hospitalisation in chronic systolic heart failure.
BACKGROUND The prognosis in patients with chronic heart failure (CHF) is poor. ST2 protein is a promising prognostic biomarker for CHF. ST2 belongs to the cardioprotective signalling pathway involving interleukin-33 and its concentration in the serum depends on the biomechanical stress of cardiomyocytes (biomechanical strain). AIM To determine the prognostic value of ST2 in short term follow-...
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تاریخ انتشار 2014